Interviews with cancer experts on prevention and screening. These are conversations, not medical advice, and the hosts have commercial sponsors. We only list episodes we'd point a friend to, and we say what each one covers. Timestamps come from each show's own notes.
Huberman Lab · Dr. Alex Marson, MD, PhD, Gladstone Institutes and UCSF · March 2026
A long conversation about how the immune system handles cancer, with a section on risk and prevention that includes BRCA.
- 30:51Smoking, BRCA, and sunlight as cancer risks. He describes cancer as a probabilistic disease, so risk builds with age.
- 38:27BRCA, mutagens, and pesticides. On BRCA, he says testing is recommended if cancer runs in your family.
- 43:57X-rays and airport scanners, charred meat, and food dyes. He says the evidence on the food items is mixed or unclear.
- 49:34How immune-based treatments like checkpoint inhibitors and CAR T-cell therapy work.
Worth knowing: It runs over two hours. The risk and prevention talk is roughly minutes 31 to 49.
The Peter Attia Drive · Episode 388 · Solo episode · April 2026
Peter Attia's case that PSA screening works better than its reputation suggests.
- 2:30Why he says current screening guidelines are failing, as advanced prostate cancer rises.
- 15:00How PSA trends, MRI, and newer imaging improve accuracy and cut down on unnecessary procedures.
- 23:00The transperineal biopsy approach, which he says improves safety and cancer detection.
- 38:00How finasteride and similar drugs lower PSA and can delay a diagnosis if they aren't accounted for.
Worth knowing: This is one physician's argument, and the guideline debate is ongoing. It doesn't cover BRCA, and the ages on our When to screen page come from NCCN, not this episode.
The Peter Attia Drive · Episode 273 · Ted Schaeffer, MD, PhD, Chair of Urology at Northwestern · October 2023
A urologist covers prostate health from urinary symptoms through cancer. The screening discussion covers PSA, MRI as a second step, and biopsy options.
- 1:37:45Genetic risk factors for prostate cancer, and using PSA to screen.
- 1:56:30A deep dive on PSA: what it is and how to read the results.
- 2:13:15MRI as a secondary screening tool, and the biopsy options.
- 2:27:00When a biopsy is needed, and how Gleason scores are interpreted.
Worth knowing: It runs over three hours, and the full show notes are behind Attia's paywall. The notes we could see don't mention BRCA.
The Dhru Purohit Show · Episode 482 · Joseph Zundell, PhD, cancer biologist and research scientist
A cancer biologist on early detection technology and the lifestyle factors linked to cancer. The guest is a researcher, not a physician, and the host isn't a clinician.
- 4:55Technology for early cancer detection.
- 22:56How obesity and visceral fat are linked to cancer.
- 28:57Exercise for building muscle and longevity.
- 35:00Protein intake and metabolism.
Worth knowing: The episode also gets into cancer as a metabolic disease, an idea that's debated in the field. The page is sponsor-supported and links to commercial scan services, so treat it as one expert's view.
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